Extracellular matrix as an inductive scaffold for functional tissue reconstruction
نویسندگان
چکیده
منابع مشابه
The extracellular matrix as a biologic scaffold for tissue engineering
● To understand the composition and organization of extracellular matrix (ECM) in tissues and organs ● To recognize the utility of scaffolds derived from ECM in the field of tissue engineering ● To comprehend the importance of mechanical behavior and mechanical design in the use of ECM scaffolds for tissue repair ● To identify the process by which ECM scaffolds are produced ● To understand some...
متن کاملExtracellular matrix scaffold for cardiac repair.
BACKGROUND Heart failure remains a significant problem. Tissue-engineered cardiac patches offer potential to treat severe heart failure. We studied an extracellular matrix scaffold for repairing the infarcted left ventricle. METHODS AND RESULTS Pigs (n=42) underwent left ventricular (LV) infarction. At 6 to 8 weeks, either 4-layer multilaminate urinary bladder-derived extracellular matrix or ...
متن کاملThe extracellular matrix as a biologic scaffold material.
Biologic scaffolds composed of naturally occurring extracellular matrix (ECM) have received significant attention for their potential therapeutic applications. The full potential of the ability of ECM scaffolds to promote constructive remodeling will not be realized, however, until an understanding of the biology and the external influences that affect biology, are better achieved. The factors ...
متن کاملDevelopment of an Acellular Tumor Extracellular Matrix as a Three-Dimensional Scaffold for Tumor Engineering
Tumor engineering is defined as the construction of three-dimensional (3D) tumors in vitro with tissue engineering approaches. The present 3D scaffolds for tumor engineering have several limitations in terms of structure and function. To get an ideal 3D scaffold for tumor culture, A549 human pulmonary adenocarcinoma cells were implanted into immunodeficient mice to establish xenotransplatation ...
متن کاملbovine articular cartilage decellularized matrix as a scaffold for use in cartilage tissue engineering
extracelllar matrix (ecm) materials from mammalian tissues have been broadly used for tissue engineering for animal models. while decellularization of tissues such as bladder, heart valve, knee meniscus and tendon has been performed, there are a few reports for articular cartilage. in this study we aimed to develop a technique to decellularize bovine articular cartilage as a biological construc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Translational Research
سال: 2014
ISSN: 1931-5244
DOI: 10.1016/j.trsl.2013.11.003